ApidCOR™

Controlled release
  • Asmus LR et al, Injectable formulations for an intravitreal sustained-release application of a novel single-chain VEGF antibody fragment, Eur J Pharm Biopharm. 2015 Mar 14.
  • Asmus LR et al, In vivo biocompatibility, sustained-release and stability of triptorelin formulations based on a liquid, degradable polymer, J Control Release. 2013 Feb 10;165(3):199-206.
  • Asmus LR, Single processing step toward injectable sustained-release formulations of Triptorelin based on a novel degradable semi-solid polymer, Eur J Pharm Biopharm. 2012 Aug;81(3):591-9.
  • Asmus LR, Solutions as solutions–synthesis and use of a liquid polyester excipient to dissolve lipophilic drugs and formulate sustained-release parenterals, Eur J Pharm Biopharm. 2011 Nov;79(3):584-91.
  • Asmus LR, Solutions for lipophilic drugs: a biodegradable polymer acting as solvent, matrix, and carrier to solve drug delivery issues, Int J Artif Organs. 2011 Feb;34(2):238-42.
  • Di Tommaso et al, Ocular biocompatibility of novel Cyclosporin A formulations based on methoxy poly(ethylene glycol)-hexylsubstituted poly(lactide) micelle carriers, Int J Pharm. 2011 Sep 20;416(2):515-24.
  • Mondon K et al, MPEG-hexPLA micelles as novel carriers for hypericin, a fluorescent marker for use in cancer diagnostics, Photochem Photobiol. 2011 Mar-Apr;87(2):399-407.
  • Di Tommaso, Investigations on the lyophilisation of MPEG-hexPLA micelle based pharmaceutical formulations, Eur J Pharm Sci. 2010 Apr 16;40(1):38-47.

ApidSOL™

Dermatology
  • Bachhav YG, Gurny R et al, Novel micelle formulations to increase cutaneous bioavailability of azole antifungals, J Control Release, 2011 Jul 30;153(2):126-32.
  • Lapteva M, Santer V, Mondon K, Patmanidis I, Chiriano G, Scapozza L, Gurny R, Möller M, Kalia YN, Targeted cutaneous delivery of cyclosporin A using micellar nanocarriers and the possible role of inter-cluster regions as molecular transport pathways. J Control Release. 2014 Dec 28;196:9-18.
  • Lapteva M, Mondon K, Möller M, Gurny R, Kalia YN, Polymeric micelle nanocarriers for the cutaneous delivery of tacrolimus: a targeted approach for the treatment of psoriasis. Mol Pharm. 2014 Sep 2;11(9):2989-3001.
Ophthalmology
  • Lallemand F et al, Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial efforts, Eur J Pharm Biopharm. 2017 117 14-28.
  • Di Tommaso C et al, A novel cyclosporin aqueous formulation for dry eye treatment: in vitro and in vivo evaluation. Invest Ophthalmol Vis Sci. 2012 Apr 30;53(4):2292-9.
  • Di Tommaso C et al, Ocular biocompatibility of novel Cyclosporin A formulations based on methoxy poly(ethylene glycol)-hexylsubstituted poly(lactide) micelle carriers. Int J Pharm. 2011 Sep 20;416(2):515-24.
  • Di Tommaso C et al, Novel micelle carriers for cyclosporin A topical ocular delivery: in vivo cornea penetration, ocular distribution and efficacy studies. Eur J Pharm Biopharm. 2012 Jun;81(2):257-64.